Anti-tumoral potential of a human granulysin-based, CEA-targeted cytolytic immunotoxin

Anti-tumoral potential of a human granulysin-based, CEA-targeted cytolytic immunotoxin

Granulysin is a protein present in the granules of human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells, with cytolytic activity against microbes and tumors. Previous work demonstrated the therapeutic effect of intratumoral injection of recombinant granulysin using in vivo models of bre...

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Bibliographic Details
Main Authors: Raquel Ibáñez-Pérez, Patricia Guerrero-Ochoa, Sameer Al-Wasaby, Rocío Navarro, Antonio Tapia-Galisteo, Diego De Miguel, Oscar Gonzalo, Blanca Conde, Luis Martínez-Lostao, Ramón Hurtado-Guerrero, Laura Sanz, Alberto Anel
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:OncoImmunology
Subjects:
granulysin
scfv
immunotoxin
cea
colon carcinoma
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1641392

Internet

http://dx.doi.org/10.1080/2162402X.2019.1641392

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