Identification of differential genomic DNA Methylation in the hypothalamus of pubertal rat using reduced representation Bisulfite sequencing

Abstract Background There are many variables affecting the onset of puberty in animals, including genetic, nutritional, and environmental factors. Recent studies suggest that epigenetic regulation, especially DNA methylation, plays a majorrole in the regulation of puberty. However, there have been n...

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Bibliographic Details
Main Authors: Lei Luo, Zhiqiu Yao, Jing Ye, Yuan Tian, Chen Yang, Xiaoxiao Gao, Min Song, Ya Liu, Yunhai Zhang, Yunsheng Li, Xiaorong Zhang, Fugui Fang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12958-017-0301-2