Thermostable and Long-Circulating Albumin-Conjugated <i>Arthrobacter globiformis</i> Urate Oxidase

Urate oxidase derived from <i>Aspergillus flavus</i> has been investigated as a treatment for tumor lysis syndrome, hyperuricemia, and gout. However, its long-term use is limited owing to potential immunogenicity, low thermostability, and short circulation time in vivo. Recently, urate o...

Full description

Bibliographic Details
Main Authors: Byungseop Yang, Inchan Kwon
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/8/1298