Thermostable and Long-Circulating Albumin-Conjugated <i>Arthrobacter globiformis</i> Urate Oxidase
Urate oxidase derived from <i>Aspergillus flavus</i> has been investigated as a treatment for tumor lysis syndrome, hyperuricemia, and gout. However, its long-term use is limited owing to potential immunogenicity, low thermostability, and short circulation time in vivo. Recently, urate o...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/8/1298 |