Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system.

Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system.

Hepatocellular carcinoma (HCC) is the most prevalent liver tumor and a deadly disease with limited therapeutic options. Dysregulation of cell signaling pathways is a common denominator in tumorigenesis, including hepatocarcinogenesis. The epidermal growth factor receptor (EGFR) signaling system is c...

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Bibliographic Details
Main Authors: Maria U Latasa, Fabiana Salis, Raquel Urtasun, Oihane Garcia-Irigoyen, Maria Elizalde, Iker Uriarte, Monica Santamaria, Francesco Feo, Rosa M Pascale, Jesús Prieto, Carmen Berasain, Matías A Avila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527604?pdf=render

Internet

http://europepmc.org/articles/PMC3527604?pdf=render

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