Obese visceral adipose dendritic cells downregulate regulatory T cell development through IL-33

Regulatory T cells (Tregs) residing in visceral adipose tissue (VAT) play a pivotal role in regulating tissue inflammation and metabolic dysfunction associated with obesity. However, the specific phenotypic and functional characteristics of Tregs in obese VAT, as well as the regulatory mechanisms sh...

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Bibliographic Details
Main Authors: Shindy Soedono, Sharlene Sharlene, Dan Hoang Nguyet Vo, Maria Averia, Eufrasia Elaine Rosalie, Yun Kyung Lee, Kae Won Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1335651/full