Develop an efficient and specific AAV-based labeling system for Muller glia in mice

Develop an efficient and specific AAV-based labeling system for Muller glia in mice

Abstract Reprogramming Müller glia (MG) into functional cells is considered a promising therapeutic strategy to treat ocular diseases and vision loss. However, current AAV-based system for MG-tracing was reported to have high leakage in recent studies. Here, we focused on reducing the leakage of AAV...

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Bibliographic Details
Main Authors: Yanxia Gao, Kailun Fang, Zixiang Yan, Haiwei Zhang, Guannan Geng, Weiwei Wu, Ding Xu, Heng Zhang, Na Zhong, Qifang Wang, Minqing Cai, Erwei Zuo, Hui Yang
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-27013-0

Internet

https://doi.org/10.1038/s41598-022-27013-0

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