Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome.

Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome.

Our laboratory has demonstrated that captopril, an angiotensin converting enzyme inhibitor, mitigates hematopoietic injury following total body irradiation in mice. Improved survival in mice is correlated with improved recovery of mature blood cells and bone marrow, reduction of radiation-induced in...

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Bibliographic Details
Main Authors: W Bradley Rittase, Elizabeth A McCart, Jeannie M Muir, Roxane M Bouten, John E Slaven, Ognoon Mungunsukh, Michelle A Bylicky, W Louis Wilkins, Sang-Ho Lee, Kristbjorn O Gudmundsson, Tiziana Di Pucchio, Cara H Olsen, Yang Du, Regina M Day
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0256208

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https://doi.org/10.1371/journal.pone.0256208

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