Transcriptome profiling of human ulcerative colitis mucosa reveals altered expression of pathways enriched in genetic susceptibility loci.

Transcriptome profiling of human ulcerative colitis mucosa reveals altered expression of pathways enriched in genetic susceptibility loci.

Human colonic mucosa altered by inflammation due to ulcerative colitis (UC) displays a drastically altered pattern of gene expression compared with healthy tissue. We aimed to understand the underlying molecular pathways influencing these differences by analyzing three publically-available, independ...

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Bibliographic Details
Main Authors: Christopher J Cardinale, Zhi Wei, Jin Li, Junfei Zhu, Mengnan Gu, Robert N Baldassano, Struan F A Grant, Hakon Hakonarson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096153&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096153&type=printable

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