Lineage-selective super enhancers mediate core regulatory circuitry during adipogenic and osteogenic differentiation of human mesenchymal stem cells

Lineage-selective super enhancers mediate core regulatory circuitry during adipogenic and osteogenic differentiation of human mesenchymal stem cells

Abstract Human mesenchymal stem cells (hMSCs) can be differentiated into osteoblasts and adipocytes. During these processes, super enhancers (SEs) play important roles. Here, we performed comprehensive characterization of the SEs changes associated with adipogenic and osteogenic differentiation of h...

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Bibliographic Details
Main Authors: Chen Wang, Wen Tian, Shou-Ye Hu, Chen-Xi Di, Chang-Yi He, Qi-Long Cao, Ruo-Han Hao, Shan-Shan Dong, Cong-Cong Liu, Yu Rong, Hua-Feng Kang, Tie-Lin Yang, Zhi Yang, Yan Guo
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05309-3

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https://doi.org/10.1038/s41419-022-05309-3

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