Lineage-selective super enhancers mediate core regulatory circuitry during adipogenic and osteogenic differentiation of human mesenchymal stem cells
Abstract Human mesenchymal stem cells (hMSCs) can be differentiated into osteoblasts and adipocytes. During these processes, super enhancers (SEs) play important roles. Here, we performed comprehensive characterization of the SEs changes associated with adipogenic and osteogenic differentiation of h...
Main Authors: | Chen Wang, Wen Tian, Shou-Ye Hu, Chen-Xi Di, Chang-Yi He, Qi-Long Cao, Ruo-Han Hao, Shan-Shan Dong, Cong-Cong Liu, Yu Rong, Hua-Feng Kang, Tie-Lin Yang, Zhi Yang, Yan Guo |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-10-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05309-3 |
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