Pharmacokinetic–Pharmacodynamic Modeling of Midazolam in Pediatric Surgery

Pharmacokinetic–Pharmacodynamic Modeling of Midazolam in Pediatric Surgery

Midazolam (MDZ) is used for sedation in surgical procedures; its clinical effect is related to its receptor affinity and the dose administered. Therefore, a pharmacokinetic–pharmacodynamic (PK-PD) population model of MDZ in pediatric patients undergoing minor surgery is proposed. A descriptive, obse...

Full description

Bibliographic Details
Main Authors: Carmen Flores-Pérez, Luis Alfonso Moreno-Rocha, Juan Luis Chávez-Pacheco, Norma Angélica Noguez-Méndez, Janett Flores-Pérez, Delfina Ortiz-Marmolejo, Lina Andrea Sarmiento-Argüello
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
midazolam
PK-PD population model
sedation
pediatrics
minor surgeries
Online Access:https://www.mdpi.com/1999-4923/15/11/2565

Internet

https://www.mdpi.com/1999-4923/15/11/2565

Similar Items