Single-cell analysis of white adipose tissue reveals the tumor-promoting adipocyte subtypes

Single-cell analysis of white adipose tissue reveals the tumor-promoting adipocyte subtypes

Abstract Background The tumor-adipose microenvironment (TAME) is characterized by the enrichment of adipocytes, and is considered a special ecosystem that supports cancer progression. However, the heterogeneity and diversity of adipocytes in TAME remains poorly understood. Methods We conducted a sin...

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Bibliographic Details
Main Authors: Si-Qing Liu, Ding-Yuan Chen, Bei Li, Zhi-Jie Gao, Hong-Fang Feng, Xin Yu, Zhou Liu, Yuan Wang, Wen-Ge Li, Si Sun, Sheng-Rong Sun, Qi Wu
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Translational Medicine
Subjects:
Tumor-adipose microenvironment
Single-cell RNA sequencing
Cancer-associated adipocytes
Adiponectin receptor
Online Access:https://doi.org/10.1186/s12967-023-04256-7

Internet

https://doi.org/10.1186/s12967-023-04256-7

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