Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine

Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine

Because of the rapid mutations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an effective vaccine against SARS-CoV-2 variants is needed to prevent coronavirus disease 2019 (COVID-19). T cells, in addition to neutralizing antibodies, are an important component of naturally acquired...

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Bibliographic Details
Main Authors: Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R. Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J. Sigal, Renhuan Xu, Huabin Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
mRNA vaccine
neutralizing antibody
T cell response
multiple T cell epitopes (MTEs)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1126392/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1126392/full

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