Apoptotic Cell Death via Activation of DNA Degradation, Caspase-3 Activity, and Suppression of Bcl-2 Activity: An Evidence-Based <i>Citrullus colocynthis</i> Cytotoxicity Mechanism toward MCF-7 and A549 Cancer Cell Lines

Apoptotic Cell Death via Activation of DNA Degradation, Caspase-3 Activity, and Suppression of Bcl-2 Activity: An Evidence-Based <i>Citrullus colocynthis</i> Cytotoxicity Mechanism toward MCF-7 and A549 Cancer Cell Lines

The objectives of this study are to investigate the cytotoxic effect of different <i>Citrullus colocynthis</i> extracts on breast and lung cancer cell lines using flow cytometry to gain mechanistic insights. <i>C. colocynthis</i> was extracted sequentially using the Soxhlet m...

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Bibliographic Details
Main Authors: Ibrahim Ahmed Shaikh, Ali Mohamed Alshabi, Saad Ahmed Alkahtani, Mohamed A. A. Orabi, Basel A. Abdel-Wahab, Ismail A. Walbi, Mohammed Shafiuddin Habeeb, Masood Medleri Khateeb, Arun K. Shettar, Joy H. Hoskeri
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Separations
Subjects:
<i>Citrullus colocynthis</i>
MCF-7
A549
apoptosis
cytotoxicity
Saudi Arabia
Online Access:https://www.mdpi.com/2297-8739/9/12/411

Internet

https://www.mdpi.com/2297-8739/9/12/411

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