A complex genetic switch involving overlapping divergent promoters and DNA looping regulates expression of conjugation genes of a gram-positive plasmid.

Plasmid conjugation plays a significant role in the dissemination of antibiotic resistance and pathogenicity determinants. Understanding how conjugation is regulated is important to gain insights into these features. Little is known about regulation of conjugation systems present on plasmids from Gr...

Full description

Bibliographic Details
Main Authors: Gayetri Ramachandran, Praveen K Singh, Juan Roman Luque-Ortega, Luis Yuste, Carlos Alfonso, Fernando Rojo, Ling J Wu, Wilfried J J Meijer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4207663?pdf=render