Mitochondrial Elongation and OPA1 Play Crucial Roles during the Stemness Acquisition Process in Pancreatic Ductal Adenocarcinoma

Mitochondrial Elongation and OPA1 Play Crucial Roles during the Stemness Acquisition Process in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer with an overall 5-year survival rate of less than 9%. The high aggressiveness of PDAC is linked to the presence of a subpopulation of cancer cells with a greater tumorigenic capacity, generically called cancer stem...

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Bibliographic Details
Main Authors: Cristian Andres Carmona-Carmona, Elisa Dalla Pozza, Giulia Ambrosini, Barbara Cisterna, Marta Palmieri, Ilaria Decimo, José M. Cuezva, Emanuela Bottani, Ilaria Dando
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
cancer stem cells
pancreatic ductal adenocarcinoma
mitochondrial dynamics
mitochondrial fusion
OPA1
Online Access:https://www.mdpi.com/2072-6694/14/14/3432

Internet

https://www.mdpi.com/2072-6694/14/14/3432

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