Limiting Monoamines Degradation Increases L-DOPA Pro-Locomotor Action in Newborn Rats

Limiting Monoamines Degradation Increases L-DOPA Pro-Locomotor Action in Newborn Rats

L-DOPA, the precursor of catecholamines, exerts a pro-locomotor action in several vertebrate species, including newborn rats. Here, we tested the hypothesis that decreasing the degradation of monoamines can promote the pro-locomotor action of a low, subthreshold dose of L-DOPA in five-day-old rats....

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Bibliographic Details
Main Authors: Inès Khsime, Marie Boulain, Abderrahman Fettah, Abdeslam Chagraoui, Gilles Courtand, Philippe De Deurwaerdère, Laurent Juvin, Grégory Barrière
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
air-stepping
monoamines
L-DOPA
spinal cord
newborn rat
Online Access:https://www.mdpi.com/1422-0067/24/19/14747

Internet

https://www.mdpi.com/1422-0067/24/19/14747

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