The experimental model of type 2 diabetes mellitus caused by a high-fat diet with low-dose streptozotocin in rats
Aim. To develop a pathogenetically reasonable model of type 2 diabetes with marked peripheral insulin resistance and relative insulin deficiency in rats using a high-fat diet and a single injection of streptozotocin in the low dose.Materials and methods. Experiments were conducted on 16 outbred male...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Siberian State Medical University (Tomsk)
2020-07-01
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Series: | Бюллетень сибирской медицины |
Subjects: | |
Online Access: | https://bulletin.ssmu.ru/jour/article/view/2858 |