The Role of Pharmacogenetics in the Therapeutic Response to Thiopurines in the Treatment of Inflammatory Bowel Disease: A Systematic Review

This study focuses on the use of thiopurines for treating inflammatory bowel diseases (IBD). These drugs undergo enzymatic changes within the body, resulting in active and inactive metabolites that influence their therapeutic effects. The research examines the role of genetic polymorphisms in the en...

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Bibliographic Details
Main Authors: Aline C. Ribeiro, Pâmela S. A. S. Gerheim, Julio Maria Fonseca Chebli, Jorge Willian L. Nascimento, Priscila de Faria Pinto
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/21/6742