The mu opioid receptor and the orphan receptor GPR151 contribute to social reward in the habenula

Abstract The mu opioid receptor (MOR) and the orphan GPR151 receptor are inhibitory G protein coupled receptors that are enriched in the habenula, a small brain region involved in aversion processing, addiction and mood disorders. While MOR expression in the brain is widespread, GPR151 expression is...

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Bibliographic Details
Main Authors: Florence Allain, Michelle Carter, Sylvie Dumas, Emmanuel Darcq, Brigitte L. Kieffer
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24395-z