Mitochondrial impairment induced by chenodeoxycholic acid: The protective effect of taurine and carnosine supplementation

<p>The cholestatic liver disease ensues with a hepatic accumulation of cytotoxic molecules. Several hydrophobic bile acids are known as cytotoxic agents accumulated in the liver during cholestasis. Chenodeoxycholic acid (CDCA) is a toxic hydrophobic bile acid. Oxidative stress and mitochondria...

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Bibliographic Details
Main Authors: Reza Heidari, Narges Abdoli, Mohammad Mehdi Ommati, Akram Jamshidzadeh, Hossein Niknahad
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2018-05-01
Series:Trends in Pharmaceutical Sciences
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/182