Decoding enhancer complexity with machine learning and high-throughput discovery
Abstract Enhancers are genomic DNA elements controlling spatiotemporal gene expression. Their flexible organization and functional redundancies make deciphering their sequence-function relationships challenging. This article provides an overview of the current understanding of enhancer organization...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-05-01
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Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-023-02955-4 |