Chronic clomipramine treatment reverses core symptom of depression in subordinate tree shrews.

Chronic stress is the major cause of clinical depression. The behavioral signs of depression, including anhedonia, learning and memory deficits, and sleep disruption, result from the damaging effects of stress hormones on specific neural pathways. The Chinese tree shrew (Tupaia belangeri chinensis)...

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Bibliographic Details
Main Authors: Jing Wang, Anping Chai, Qixin Zhou, Longbao Lv, Liping Wang, Yuexiong Yang, Lin Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312510/?tool=EBI