Hepatic lipase facilitates the selective uptake of cholesteryl esters from remnant lipoproteins in apoE-deficient mice

We have investigated the role of hepatic lipase (HL) in remnant lipoprotein metabolism independent of lipolysis by using recombinant adenovirus to express native and catalytically inactive HL (HL-145G) in apolipoprotein (apo)E-deficient mice characterized by increased plasma concentrations of apoB-4...

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Main Authors: Marcelo J.A. Amar, Klaus A. Dugi, Changting C. Haudenschild, Robert D. Shamburek, Bernhard Foger, Michael Chase, Andre Bensadoun, Robert F. Hoyt, Jr., H. Bryan Brewer, Jr., Silvia Santamarina-Fojo
Format: Article
Language:English
Published: Elsevier 1998-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033323X