Safety and efficacy of autologous cell vaccines in solid tumors: a systematic review and meta-analysis of randomized control trials

Abstract We conducted a systematic review and meta-analysis of randomized control trials to formally assess the safety and efficacy of autologous whole cell vaccines as immunotherapies for solid tumors. Our primary safety outcome was number, and grade of adverse events. Our primary efficacy outcome...

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Bibliographic Details
Main Authors: Donald J. Bastin, Joshua Montroy, Michael A. Kennedy, Andre B. Martel, Risa Shorr, Maryam Ghiasi, Dominique M. Boucher, Boaz Wong, Louise Gresham, Jean-Simon Diallo, Dean A. Fergusson, Manoj M. Lalu, Natasha Kekre, Rebecca C. Auer
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29630-9