DNA damage responses and oxidative stress in dyskeratosis congenita.

DNA damage responses and oxidative stress in dyskeratosis congenita.

Dyskeratosis congenita (DC) is an inherited multisystem disorder of premature aging, cancer predisposition, and bone marrow failure caused by selective exhaustion of highly proliferative cell pools. DC patients also have a poor tolerance to chemo/radiotherapy and bone marrow transplantation. Althoug...

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Bibliographic Details
Main Authors: Larisa Pereboeva, Erik Westin, Toral Patel, Ian Flaniken, Lawrence Lamb, Aloysius Klingelhutz, Frederick Goldman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790691?pdf=render

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http://europepmc.org/articles/PMC3790691?pdf=render

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