Contractility of isolated colonic smooth muscle strips from rats treated with cancer chemotherapy: differential effects of cisplatin and vincristine

BackgroundCertain antineoplastic drugs cause gastrointestinal disorders even after the end of treatment. Enteric neuropathy has been associated with some of these alterations. Our goal was to assess the impact of repeated treatment with cisplatin and vincristine on the contractility of circular and...

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Main Authors: Yolanda López-Tofiño, Luis Felipe Barragán del Caz, David Benítez-Álvarez, Paula Molero-Mateo, Kulmira Nurgali, Gema Vera, Ana Bagües, Raquel Abalo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1304609/full