Biological evaluation of selected metronidazole derivatives as anti-nitroreductase via in silico approach
The 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (2HMN) is a powerful antibacterial and antiparasitic drug used alongside other drugs against Helicobacter pylori infection and was investigated the effects of substituents: –OH (A), H (B), –SPh (C), –COOH (D), –NO2 (E) and –OCH3 (F) on the interaction...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade Estadual Paulista
2022-10-01
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| Series: | Eclética Química |
| Subjects: | |
| Online Access: | https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/1322 |