Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through peroxisome proliferator-activated receptor γ-dependent mechanism in Alzheimer's disease

Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by the deposition of β-amyloid (Aβ) peptides and dysfunction of mitochondrion, which result in neuronal apoptosis and ultimately cognitive impairment. Inhibiting Aβ generation and repairing mitochondrial damage a...

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Bibliographic Details
Main Authors: Zhijun He, Xiaoqian Li, Zi Wang, Yingqi Cao, Shuangxue Han, Nan Li, Jie Cai, Shuiyuan Cheng, Qiong Liu
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723002495