NR2F1 Regulates TGF-β1-Mediated Epithelial-Mesenchymal Transition Affecting Platinum Sensitivity and Immune Response in Ovarian Cancer

NR2F1 Regulates TGF-β1-Mediated Epithelial-Mesenchymal Transition Affecting Platinum Sensitivity and Immune Response in Ovarian Cancer

The mechanism underlying platinum resistance in ovarian cancer (OC) remains unclear. We used bioinformatic analyses to screen differentially expressed genes responsible for platinum resistance and explore NR2F1′s correlation with prognostic implication and OC staging. Moreover, Gene-set enrichment a...

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Bibliographic Details
Main Authors: Qiuju Liang, Zhijie Xu, Yuanhong Liu, Bi Peng, Yuan Cai, Wei Liu, Yuanliang Yan
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
ovarian cancer
platinum resistance
NR2F1
TGF-β1
EMT
CAF
Online Access:https://www.mdpi.com/2072-6694/14/19/4639

Internet

https://www.mdpi.com/2072-6694/14/19/4639

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