Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis

Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis

Abstract Background Idiopathic Pulmonary Fibrosis (IPF) is an age-associated progressive lung disease with accumulation of scar tissue impairing gas exchange. Previous high-throughput studies elucidated the role of cellular heterogeneity and molecular pathways in advanced disease. However, critical...

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Bibliographic Details
Main Authors: Minxue Jia, Lorena Rosas, Maria G. Kapetanaki, Tracy Tabib, John Sebrat, Tamara Cruz, Anna Bondonese, Ana L. Mora, Robert Lafyatis, Mauricio Rojas, Panayiotis V. Benos
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Respiratory Research
Subjects:
Idiopathic Pulmonary Fibrosis
Fibroblasts
Copper
Ribosomal proteins
MOXD1
scRNA-seq
Online Access:https://doi.org/10.1186/s12931-023-02419-0

Internet

https://doi.org/10.1186/s12931-023-02419-0

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