In situ immunomodulation of tumors with biosynthetic bacteria promote anti-tumor immunity

In situ immunomodulation of tumors with biosynthetic bacteria promote anti-tumor immunity

Immune checkpoint blockade (ICB) therapy potently revives T cell's response to cancer. However, patients suffered with tumors that had inadequate infiltrated immune cells only receive limited therapeutic benefits from ICB therapy. Synthetic biology promotes the alternative strategy of harnessin...

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Bibliographic Details
Main Authors: Zhongda Lin, Fanqiang Meng, Yumeng Ma, Chi Zhang, Zhirang Zhang, Zhaoxin Yang, Yuan Li, Linlin Hou, Yuzhong Xu, Xin Liang, Xudong Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-02-01
Series:Bioactive Materials
Subjects:
Salmonella
GM-CSF
IL-7
Synthetic biology
Cancer immunotherapies
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23002785

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http://www.sciencedirect.com/science/article/pii/S2452199X23002785

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