Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA.

Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA.

Increased PDGFRA signaling is an essential pathogenic factor in many subtypes of gliomas. In this context the cell surface expression of PDGFRA is an important determinant of ligand sensing in the glioma microenvironment. However, the regulation of spatial distribution of PDGFRA in glioma cells rema...

Full description

Bibliographic Details
Main Authors: Dongfeng Chen, Duo Zuo, Cheng Luan, Min Liu, Manli Na, Liang Ran, Yingyu Sun, Annette Persson, Elisabet Englund, Leif G Salford, Erik Renström, Xiaolong Fan, Enming Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906156?pdf=render

Internet

http://europepmc.org/articles/PMC3906156?pdf=render

Similar Items