Case report: Extraskeletal Ewing sarcoma with a germline pathogenic variant of SMARCA4

Case report: Extraskeletal Ewing sarcoma with a germline pathogenic variant of SMARCA4

SMARCA4 (BRG1) is a core unit of the SWI/SNF complex, regulating gene transcription through chromatin remodeling. Germline SMARCA4 variants have been reported to be associated with various malignancies. Here, we report the first case of extraskeletal Ewing sarcoma in a young female patient with a ge...

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Bibliographic Details
Main Authors: Min-Chae Kang, Sun-Young Kong, Sang-Yoon Park, Seog-Yun Park, Eun-Gyeong Lee, Chong Woo Yoo, Yun Hwan Kim, Hyeji Kim, Wonyoung Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
Ewing sarcoma
genetic counseling
SMARCA4 mutation
Next-generation sequence (NGS)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1422605/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1422605/full

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