Iron status and systemic inflammation, but not gut inflammation, strongly predict gender-specific concentrations of serum hepcidin in infants in rural Kenya.

Hepcidin regulation by competing stimuli such as infection and iron deficiency has not been studied in infants and it's yet unknown whether hepcidin regulatory pathways are fully functional in infants. In this cross-sectional study including 339 Kenyan infants aged 6.0±1.1 months (mean±SD), we...

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Bibliographic Details
Main Authors: Tanja Jaeggi, Diego Moretti, Jane Kvalsvig, Penny A Holding, Harold Tjalsma, Guus A M Kortman, Irma Joosten, Alice Mwangi, Michael B Zimmermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3583867?pdf=render