Conformational plasticity of proNGF.

Nerve Growth Factor is an essential protein that supports neuronal survival during development and influences neuronal function throughout adulthood, both in the central and peripheral nervous system. The unprocessed precursor of NGF, proNGF, seems to be endowed with biological functions distinct fr...

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Bibliographic Details
Main Authors: Francesca Paoletti, Francesca Malerba, Geoff Kelly, Sylvie Noinville, Doriano Lamba, Antonino Cattaneo, Annalisa Pastore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3144226?pdf=render