Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway

Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway

It has been established for almost 30 years that the retinoic acid receptor (RAR) signalling pathway plays essential roles in the morphogenesis of a large variety of organs and systems. Here, we used a temporally controlled genetic ablation procedure to precisely determine the time windows requiring...

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Bibliographic Details
Main Authors: Marius Teletin, Manuel Mark, Olivia Wendling, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Yann Herault, Norbert B. Ghyselinck
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomedicines
Subjects:
mouse
heart development
lung development
eye development
inner ear development
axial rotation
Online Access:https://www.mdpi.com/2227-9059/11/1/198

Internet

https://www.mdpi.com/2227-9059/11/1/198

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