Small Conductance Ca2 +-Activated K+ (SK) Channel mRNA Expression in Human Atrial and Ventricular Tissue: Comparison Between Donor, Atrial Fibrillation and Heart Failure Tissue

Small Conductance Ca2 +-Activated K+ (SK) Channel mRNA Expression in Human Atrial and Ventricular Tissue: Comparison Between Donor, Atrial Fibrillation and Heart Failure Tissue

In search of more efficacious and safe pharmacological treatments for atrial fibrillation (AF), atria-selective antiarrhythmic agents have been promoted that target ion channels principally expressed in the atria. This concept allows one to engage antiarrhythmic effects in atria, but spares the vent...

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Bibliographic Details
Main Authors: Elisa Darkow, Thong T. Nguyen, Marina Stolina, Fabian A. Kari, Constanze Schmidt, Felix Wiedmann, István Baczkó, Peter Kohl, Sridharan Rajamani, Ursula Ravens, Rémi Peyronnet
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
RNA-seq
SK channels
AF marker genes
atria-selective drugs
atrial fibrillation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.650964/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.650964/full

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