Fatty liver is associated with transcriptional downregulation of stearoyl-CoA desaturase and impaired protein dimerization.

AIMS AND METHODS: We evaluated the modulation of liver stearoyl-CoA desaturase-1 (Scd1) by dietary factors and insulin resistance (IR) in two experimental models of high-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD). The first model included Sprague Dawley (SD) rats that developed...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Tomas Fernández Gianotti, Adriana Burgueño, Noelia Gonzales Mansilla, Carlos Jose Pirola, Silvia Sookoian
स्वरूप: लेख
भाषा:English
प्रकाशित: Public Library of Science (PLoS) 2013-01-01
श्रृंखला:PLoS ONE
ऑनलाइन पहुंच:http://europepmc.org/articles/PMC3786952?pdf=render