Fatty liver is associated with transcriptional downregulation of stearoyl-CoA desaturase and impaired protein dimerization.
AIMS AND METHODS: We evaluated the modulation of liver stearoyl-CoA desaturase-1 (Scd1) by dietary factors and insulin resistance (IR) in two experimental models of high-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD). The first model included Sprague Dawley (SD) rats that developed...
मुख्य लेखकों: | , , , , |
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स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
Public Library of Science (PLoS)
2013-01-01
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श्रृंखला: | PLoS ONE |
ऑनलाइन पहुंच: | http://europepmc.org/articles/PMC3786952?pdf=render |