Intelligently responsive amphiphilic small molecule loaded with doxorubicin to form highly effective anti-hepatocarcinoma nanomicelles

Nanodrug self-assembled by amphiphilic small molecules were proved to be important resource of medicine. In this study, a nanodrug of hydrophobic doxorubicin (DOX)linked to lactose (Lac) via pH sensitive acylhydrazide bond was used as a carrier to entrap the hydrophobic doxorubicin to form drug-load...

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Bibliographic Details
Main Authors: Chunxiao Gao, Yuanyuan Ma, Deyue Yan, Lianzhen Chen, Wei Yuan, Jie Ma
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127521007851