Protein Prenyltransferases and Their Inhibitors: Structural and Functional Characterization

Protein Prenyltransferases and Their Inhibitors: Structural and Functional Characterization

Protein prenylation is a post-translational modification controlling the localization, activity, and protein–protein interactions of small GTPases, including the Ras superfamily. This covalent attachment of either a farnesyl (15 carbon) or a geranylgeranyl (20 carbon) isoprenoid group is catalyzed b...

Full description

Bibliographic Details
Main Authors: Aleksandra Marchwicka, Daria Kamińska, Mohsen Monirialamdari, Katarzyna M. Błażewska, Edyta Gendaszewska-Darmach
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
prenyltransferases
structures
inhibitors
Online Access:https://www.mdpi.com/1422-0067/23/10/5424

Internet

https://www.mdpi.com/1422-0067/23/10/5424

Similar Items