In Vitro–In Vivo Correlation of Posaconazole–Amphotericin B Combination against <i>Candida albicans</i>: In Vitro Interacting Concentrations Are Associated with In Vivo Free Drug Levels

In Vitro–In Vivo Correlation of Posaconazole–Amphotericin B Combination against <i>Candida albicans</i>: In Vitro Interacting Concentrations Are Associated with In Vivo Free Drug Levels

The in vitro/in vivo correlation of antifungal combination testing is necessary in order to assess the efficacy of combination regimens. We, therefore, attempted to correlate in vitro chequerboard testing of posaconazole (POS) and amphotericin B (AMB) with the in vivo outcome of combination therapy...

Full description

Bibliographic Details
Main Authors: Joseph Meletiadis, Maria-Ioanna Beredaki, Antigoni Elefanti, Spyros Pournaras, Anouk Muller
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Fungi
Subjects:
amphotericin B
posaconazole
combination therapy
<i>Candida albicans</i>
in vitro–in vivo correlation
Online Access:https://www.mdpi.com/2309-608X/9/4/434

Internet

https://www.mdpi.com/2309-608X/9/4/434

Similar Items