Highly efficient multiplex base editing: One-shot deactivation of eight genes in Shewanella oneidensis MR-1

Highly efficient multiplex base editing: One-shot deactivation of eight genes in Shewanella oneidensis MR-1

Obtaining electroactive microbes capable of efficient extracellular electron transfer is a large undertaking for the scalability of bio-electrochemical systems. Inevitably, researchers need to pursue the co-modification of multiple genes rather than expecting that modification of a single gene would...

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Bibliographic Details
Main Authors: Yaru Chen, Meijie Cheng, Yan Li, Lin Wang, Lixia Fang, Yingxiu Cao, Hao Song
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-03-01
Series:Synthetic and Systems Biotechnology
Subjects:
Multiplex gene editing
Electroactive microorganisms
Base editing
Multiplexed engineering
CRISPR
Extracellular electron transfer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X22001004

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http://www.sciencedirect.com/science/article/pii/S2405805X22001004

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