Maintenance of PKMζ-modulated synaptic efficacies despite protein turnover

How can synaptic efficacies be maintained despite the fast turnover of proteins at synapses? Partially, we know that the synthesis of new proteins is essential for the induction of the late, long-lasting phase of long-term potentiation (L-LTP). Recent experiments suggest that the concentration of pr...

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Bibliographic Details
Main Author: Naveed Aslam
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Systems Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsysb.2022.933938/full