IFN‐γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL‐23/IL‐17 axis in chronic hepatitis B virus infection

IFN‐γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL‐23/IL‐17 axis in chronic hepatitis B virus infection

Abstract Objectives This study aimed to determine the role of CD161+CD4+ T cells in chronic hepatitis B virus (HBV) infection. Methods A total of 94 patients with chronic hepatitis B (CHB), 73 with liver cirrhosis (LC) and 28 healthy controls were enrolled to determine frequency, cytokine production...

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Bibliographic Details
Main Authors: Jing Li, Lisha Cheng, Haoyu Jia, Chun Liu, Siqi Wang, Yun Liu, Yue Shen, Shengdi Wu, Fanli Meng, Beishi Zheng, Changqing Yang, Wei Jiang
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
CD161+CD4+ T cells
interferon‐γ
interleukin 17
liver fibrosis
HBV
Online Access:https://doi.org/10.1002/cti2.1353

Internet

https://doi.org/10.1002/cti2.1353

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