Single Cell Analysis of Cultivated Fibroblasts from Chronic Pancreatitis and Pancreatic Cancer Patients

Single Cell Analysis of Cultivated Fibroblasts from Chronic Pancreatitis and Pancreatic Cancer Patients

Cancer-associated fibroblasts (CAFs) play a major role in the progression and drug resistance of pancreatic cancer. Recent studies suggest that CAFs exhibit functional heterogeneity and distinct transcriptomic signatures in pancreatic cancer. Pancreatic fibroblasts also form an integral component in...

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Bibliographic Details
Main Authors: Yoshiaki Sunami, Yijun Chen, Bogusz Trojanowicz, Matthias Sommerer, Monika Hämmerle, Roland Eils, Jörg Kleeff
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
cancer-associated fibroblasts
pancreatic cancer
chronic pancreatitis
single-cell RNA sequencing
cellular plasticity
Online Access:https://www.mdpi.com/2073-4409/11/16/2583

Internet

https://www.mdpi.com/2073-4409/11/16/2583

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