Acute fluoxetine treatment induces slow rolling of leukocytes on endothelium in mice.

Acute fluoxetine treatment induces slow rolling of leukocytes on endothelium in mice.

Activated platelets release serotonin at sites of inflammation where it acts as inflammatory mediator and enhances recruitment of neutrophils. Chronic treatment with selective serotonin reuptake inhibitors (SSRI) depletes the serotonin storage pool in platelets, leading to reduced leukocyte recruitm...

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Bibliographic Details
Main Authors: Nadine Herr, Maximilian Mauler, Thilo Witsch, Daniela Stallmann, Stefanie Schmitt, Julius Mezger, Christoph Bode, Daniel Duerschmied
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3919751?pdf=render

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http://europepmc.org/articles/PMC3919751?pdf=render

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