Design of Oligourea-Based Foldamers with Antibacterial and Antifungal Activities

Design of Oligourea-Based Foldamers with Antibacterial and Antifungal Activities

There is an urgent need to develop new therapeutic strategies to fight the emergence of multidrug resistant bacteria. Many antimicrobial peptides (AMPs) have been identified and characterized, but clinical translation has been limited partly due to their structural instability and degradability in p...

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Bibliographic Details
Main Authors: Lorène Tallet, Emilie Frisch, Mégane Bornerie, Claire Medemblik, Benoît Frisch, Philippe Lavalle, Gilles Guichard, Céline Douat, Antoine Kichler
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
amphiphilic cationic foldamers
oligoureas
oligourea-peptide hybrids
antibacterial activity
antifungal properties
Online Access:https://www.mdpi.com/1420-3049/27/5/1749

Internet

https://www.mdpi.com/1420-3049/27/5/1749

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