Ubiquitin and ubiquitin-like molecules in DNA double strand break repair

Abstract Both environmental and endogenous factors induce various forms of DNA damage. DNA double strand break (DSB) is the most deleterious DNA lesion. The swift initiation of a complexed network of interconnected pathways to repair the DNA lesion is essential for cell survival. In the past years,...

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Bibliographic Details
Main Authors: Jia Yu, Bo Qin, Zhenkun Lou
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-020-0380-1