Magnesium hydroxide versus macrogol/electrolytes in the prevention of opioid-induced constipation in incurable cancer patients: study protocol for an open-label, randomized controlled trial (the OMAMA study)

Abstract Background Opioid-induced constipation (OIC) is a common symptom in cancer patients treated with opioids with a prevalence of up to 59%. International guidelines recommend standard laxatives such as macrogol/electrolytes and magnesium hydroxide to prevent OIC, although evidence from randomi...

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Main Authors: K.R.J. Kistemaker, A. de Graeff, M. Crul, G. de Klerk, P.M. van de Ven, M.P. van der Meulen, L. van Zuylen, M.A.H. Steegers
格式: Article
語言:English
出版: BMC 2023-03-01
叢編:BMC Palliative Care
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在線閱讀:https://doi.org/10.1186/s12904-023-01143-2